Hi,
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Here is my list of the weirdest issues I have experienced with SharePoint Online. Some of them are also reproduceable on-prem, some are not. I don't know if these are bugs or "by design" issues.
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List with unique permissions in App Web
Did you know that if you want to have list with unique permissions in an App-Web (being part of an Add-In deployment), you must ask at least the Manage List permission in the App Manifest.